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Contact lens sugar monitoring
 
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Contact lenses that warn diabetics of dangerous blood sugar levels to be developed                                     

A £120,000 research grant has been awarded to research and develop contact lenses that use “Sensor Hologram”          technology to help diabetics ensure their blood sugar levels are not dangerously high or                                           low.                                                                                                                                                                    
                                                                                                                                                                          
The funding will pay for a researcher to be employed for two years to help develop the new system, which                    automatically senses the glucose levels of diabetics so that they will no longer have to take blood samples daily.        

The researcher will work for Smart Holograms, based in Cambridge , which is developing the sensors, but will also be    supervised by Dr Tony James and Dr Steve Bull of the University of Bath ’s Department of Chemistry. Dr James is an    expert on sensors for glucose and Dr Bull is an expert in organic synthesis.                                                             

  Dr James said that at present some diabetics have to take bloods samples several times a day by pricking                 themselves with a needle and checking the sample’s glucose level using an electronic kit.                                         

  This is necessary because the glucose level in a diabetic’s blood can rise or fall too much, which can cause coma or other health problems. However, taking the samples is painful and inconvenient.                                                       

  The new system involves special contact lenses which sense the glucose levels in the tear fluid of the wearer’s eye,    which may be linked to the concentration of glucose in the blood.                                                                            

  Changes in the glucose level in the tear fluid alter the wavelength of light reflected by the “Sensor Hologram” in the       contact lens, and this can be detected by a small device held up to the eye to give an accurate reading of the wearer’s glucose level. This painless system will allow diabetics to monitor their glucose levels more often, leading to better       blood sugar control and fewer health problems.                                                                                                       

  “This method is the most sensitive of all of the systems that are being developed for diabetics,” said Dr James.           "When it comes onto the market it will make the lives of many millions of diabetics simpler, safer and less painful.”     

  The research team from Bath will work on developing a chemical receptor which will be incorporated into the contact    lens and which will only interact with glucose to produce a change in the hologram is produced.                                 

  The grant is jointly funded by Smart Holograms and the Department of Trade and Industry under its Knowledge           Transfer Partnership (KTP) scheme. Dr James and Dr Bull were helped by Richard Battams, the University’s KTP        Programme Manager.                                                                                                                                           

  Smart Holograms, which has an investment of £17 million in its work, has a team of 25 people and facilities in            Cambridge , UK , and San Ramon , USA . It is also planning to open a commercial office in Boston , USA , later this         year.                                                                                                                                                                   

For further information, please contact:                                                                                                            

Smart Holograms:  +44 (0)1223 393403, email: Info@SmartHolograms.com, Website:                                                http://www.SmartHolograms.com.                                                                                                                          

Smart Holograms is an early-stage company that has exclusive rights to the sensor hologram technology invented at Cambridge University . To date, Smart has had an investment of £17 million in its core science base and in the             business. The Company currently has a team of 25 people (including 10 with PhD) and has two facilities: in                 Cambridge (UK) and in San Ramon (USA). Smart is also planning to open a new Commercial office in Boston later      this year. In addition, it has four partnerships with global, leading companies for exploitation of its novel sensor             hologram technology. The company is currently doubling its head count and aims to be completing development of its first products in 2006.                                                                                                                                           

John Pritchard PhD MBA (Chief Technical Officer) has over twenty years of international management experience      from companies such as Boehringer Mannheim, Genzyme and Hypoguard. At Boehringer Mannheim he was               responsible for the development of the first generation biosensor test strip for the Accuchek® Advantage™ blood         glucose monitoring system. He has a PhD in Biochemistry from Liverpool University and an MBA from Boston              University . John joined Smart in November 2005                                                                                                     

(4/3/06)