Education - Pollution update, 6.03

THE AUTISM & MULTIPLE SCLEROSIS PROCESS.

1. INCREASED MERCURY EXPOSURE AT YOUNGER AGE.

Thiomersal in DTP (25 ug.mercury per dose), DT, Tetanus, Hepatitis B & (most)

influenza vaccines, content of some fish, and emissions from industrial chimneys including incinerators, waste-burning cement works & crematoria have led to an ever higher body burden of mercury at a younger and younger age. A relative shortage of zinc in the diet precludes the formation of metallothionine hence preventing the mercury being excreted via the urine. Mercury opens up the blood/brain and blood/bowel bafflers, hypes the immune system and acts on various brain processes in a harmful way. The process is compounded by a herbicide and exposure to lead. Levels of mercury inhaled at UK schools have reached around 1 ug/m3 PM2.5 size in Derbyshire and probably higher elsewhere. Mercury can induce alteration of genes affecting astrocyte differentiation and regional brain glial fibrillary acidic protein so that autoimmune reactions can occur with raised IgG affecting neurofilaments and myelin basic protein. These antibodies correlate with sensorimotor deficits and neuromuscular function. Neurotoxicants have been demonstrated in 90% of autistic children resulting from autoantibodies produced by haptens formed by the mercury or other toxin attaching to brain proteins potentiated by the opened blood-brain barrier. OP pesticides also open up the blood/brain barrier. Vojdani has detected antibodies to 9 different neuron-specific antigens in the sera of autistic children. ELISA assays determined serum IgA, IgM and IgG levels against the antigens.

2. LOW T-LYMPHOCYTE LEVELS from HIGH PM2 5 AIR POLLUTION.

Use of hazardous (effectively waste) mixes as fuel in the UK since 1992 in incinerators, cement works, trains, oil refineries and other industry has vastly increased PM2.5 air pollution, recently measured at 600ug/m3 in the UK (USEPA annual limit 15ug/m3). 90% of those particles size PM1 are retained in the lung and are dealt with by macrophages and T-lymphocytes. The depletion of the T-lymphocytes leaves the victim vulnerable to infections and had reactions to multiple live vaccines such as MMR Studies have already revealed a marked drop in T-lymphocytes in many recipients of Tetanus and MMR vaccines. Hence a study near a Belgian incinerator complying with EC directives found almost 90% of boys aged 2 to 9 years suffering from assorted illnesses. Infections such as otitis would be treated with antibiotics, many of which lead to alteration in bowel flora including candida or clostridium or new infections including streptococcus, mycoplasma or HHV-6 can be acquired or MMR-measles virus would start up a bowel wall inflammation if the level of T-lymphocytes was inadequate to cope with the viral load injected.

3. BOWEL WALL INFLAMMATION and SHORT CHAIN PEPTIDES.

Antibiotics may alter bowel flora, for example inducing candida overgrowth (unless probiotics or nystatin are given). Low T-lymphocyte levels may allow the development of new predominant bowel bacteria or viruses. A low grade bowel wall inflammation results, reducing production of secretin, leading to reduction in pancreatic proteinase enzymes, resulting in inadequate digestion of especially milk protein and wheat gluten. Milk butyrophilin and other short chain peptides are then absorbed from the inflamed bowel wall into the blood becoming antigens and opiate like agents. Auto-antibodies are then carried into the brain along with the relevant virus/bacteria enabled by that opened blood/brain barrier, cross-reacting with brain proteins. MMR administration produces increased cytokine interferon-gamma. With inadequate I-lymphocytes and/or inadequate vitamin A, an overaction of interferon gamma occurs found at 30 times controls in autistic children. If the child receiving MMR still has a high rubella antibody titre from the mother, an added immunological inflammatory response occurs- Development of autism takes time due to the need for adequate build-up of auto-antibodies in the brain to cause clinical effects. Lower levels account for less acute syndromes. This process is identical for autism, multiple sclerosis and Guillain-Barre Syndrome with different viruses and peptide chains. The coeliac disease process is also similar except that it involves bowel only rather than the brain.

TREATMENT OPTIONS medically include detox following analysis of toxins and preferably ELISA findings where available. In most cases zinc administration is required for at least 6 weeks. Other medicaments such as coenzyme Q10 (to assist mitochondria of brain cells, assist immune system to deal with candida, and to act as anti-inflammatory antihistamine), glyconutrients (?xylitol being the most active ingredient), and vitamin B6 (to prevent pentosidine formation which is involved in various conditions including Alzheimers) amongst others have been used in treating autistic children with varying success. These findings explain the processes involved and concur with patient experience. The diet must be modified and enzymes added in the worst victims.